Over the past years the questions of managing the interface between different facilities in inpatient, partly inpatient, ambulant and familial fields got into the centre of interest. Care- and case management can resolve these complex interface problems. However, taking over responsibility for a case needs co-operation and co-ordination within the facilities, the implementation of assessments, optimised transition procedures, guided programmes and the education of the patients and their families. At this, Nursing is assigned to a new key role by different sides. With Nursing taking over case-responsibility, the expertise is diverting towards economic, legal and administrative portfolios. In the future, Nursing will have to adjust to a triangular area of conflict between Nursing, Care and Case-Management. In addition, there will be medical tasks that need to be done self dependently. At this, the traditional interfaces between the tasks of physicians and nurses and the corresponding competences need to be re-organised. These new competences will be acquired in the university system and will lead to new occupational profiles (e.g. Advanced Nursing Practitioner, Physician Assistance). They will substitute the traditional advanced vocational training.This relocating of Nursing and the corresponding shifting of expertise within and between the different professional groups in the health care system are shown in a „model of current and future shifts of expertise around the profession of Nursing”.